Feline Infectious Peritonitis – neurotropic

Feline Infectious Peritonitis- neurotropic
History: A 7 month old female intact DSH kitten had neurologic signs and seizures in the past few months (Along with several others from a shelter).  This particular kitten presented for circling and ataxia.
Gross Findings:
Gross lesions were limited to multifocal petechiae  in the white matter of the cerebellum.
Histopathology:
Brain:  There are moderate numbers of lymphocytes, [...]

Diffuse soft tissue mineralization in a cat

Diffuse Soft Tissue Mineralization in a Cat
Contributer: C. Ganta
History: A five month old female domestic short hair cat had chronic cough which was non-responsive to antibiotics or vaccines. Tracheal wash bacterial culture was negative, mycoplasma by PCR was negative and toxoplasma serology was negative.
Gross Lesions:
Lungs: The lungs failed to collapse and were white, firm, [...]

Splenic Hemangisarcoma in a Cat

Splenic Hemangiosarcoma in a cat:
History: A 13 year old cat was was diagnosed with anemia and an abdominal mass. A fine needle aspirate cytology was consistent with a mesenchymal neoplasia.
Gross Findings:
Histopathology:
Spleen: There are broad sheets of large numbers of polygonal to round cells with abundant eosinophilic cytoplasm that occasionally form blood [...]

Aplasia of the Major Duodenal Papilla in a Feline

 
Aplasia of the Major Duodenal Papilla or Bile Duct Atresia in a feline kitten
History: A 2 month old kitten died acutely with no previous clinical signs. FIV and FeLV tests were negative.
Gross Lesions: The kitten was very thin with little muscle mass or body fat stores. The gall bladder was markedly enlarged and [...]

Histoplasmosis in a Cat- Histoplasma capsulatum

History: A 4 year old cat had been inappetant for 3 weeks with normal CBC/ CHEM. It was treated with Depo-Medrol and 2 weeks later was severely dyspneic and had anisocoria.
Gross Findings:
Lungs: Multifocal to coalescing granulomas throughout the lung
Spleen: Focal granuloma
Meninges: Diffuse suppurative meningitis
Comment: An impression smear was made of [...]

Tyzzer’s Disease in a Feline

Answer: Whats your diagnosis # 1
this page was originally posted as WYD # 1, click below for the original page or scroll down for the rest of the information.
View original page with history
Multifocal hepatic necrosis

Warthin Starry Silver stain.

Clostridium piliforme is visible at the edge of necrotic areas. We also found focal transmural necrosis of the [...]

Whats Your Diagnosis #1

Whats your diagnosis? #1 (last updated July 10th)

A 3 week old DSH kitten died suddenly after 2 days of diarrhea.

Differential Diagnosis for Multifocal liver necrosis in a kitten:
Viral:
FIP
Bacterial:
Salmonellosis
Tularemia
Yersinia spp
Nocardia spp
E. coli
Clostridium piliforme
Protozoal:
Toxoplasma gondii
Fungal:
Histoplasmosis
Here are the histo pics:

There are multifocal areas of necrosis with very little associated inflammation in the liver. We [...]