Histoplasmosis in a Cat- Histoplasma capsulatum


History: A 4 year old cat had been inappetant for 3 weeks with normal CBC/ CHEM. It was treated with Depo-Medrol and 2 weeks later was severely dyspneic and had anisocoria.

Gross Findings:

Lungs: Multifocal to coalescing granulomas throughout the lung

Lung, multifocal to coalescing granulomas

Lung, multifocal to coalescing granulomas

Gordon Andrews

Lung, cut section with granulomas

Spleen: Focal granuloma

Meninges: Diffuse suppurative meningitis

Brain, diffuse meningitis

Brain, diffuse meningitis

Comment: An impression smear was made of a cut surface of lung. Numerous macrophages were filled with 3-4 micrometer fungal organisms characteristic of Histoplasma capsulatum.

Gordon Andrews

Cytology: Intracellular fungi

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About Brian

Anatomic Pathologist, VetPath Services, Stone Ridge, NY- musculoskeletal, oral/dental, and sinonasal diseases
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