History: A 4 year old cat had been inappetant for 3 weeks with normal CBC/ CHEM. It was treated with Depo-Medrol and 2 weeks later was severely dyspneic and had anisocoria.
Lungs: Multifocal to coalescing granulomas throughout the lung
Spleen: Focal granuloma
Meninges: Diffuse suppurative meningitis
Comment: An impression smear was made of a cut surface of lung. Numerous macrophages were filled with 3-4 micrometer fungal organisms characteristic of Histoplasma capsulatum.