Tularemia in a cat and capybara
This post combines two cases Tularemia: the cat and capybara have no relation
History: A 2 year-old male DSH cat had a leg wound 1 week prior, then stopped eating and drinking, became laterally recumbent and depressed. Temperature, pulse and respiration were within normal limits, PCV was 22% with a neutrophilic leukocytosis and left shift. The capybara was a captive zoo animal living with several capybaras. Several had severe bloody diarrhea and one died. It was necropsied by the referring veterinarian who described necrotizing enteritis as the primary gross lesion and submitted fixed tissues for histopathology.
Cat: The sclera was icteric, and the left hind-limb hada 2 cm ulcer over the left lateral aspect of the tarsus and tibia with swollen subcutis. The spleen contained many 1mm diameter white foci that were ell-circumscribed. The liver contained many 1mm white foci. The lung was edematous, dark red, and contained many 2-3mm white foci. The intestines contained tarry black feces but no other lesions. Many lymph nodes were necrotic with white foci.
Spleen: Multifocal random necrotizing suppurative splenitis, severe
Liver: Multifocal necro-suppurative hepatitis, moderate, generalized
Skin: Focal necrotizing panniculitis, and ulcerative dermatitis with vascular thrombosis
Lymph nodes: Diffuse necro-suppurative lymphadenitis, severe
Lungs: Multifocal necro-suppurative pneumonia
Stomach: Suppurative gastritis, multifocal, mild
Large intestine: Intraluminal hemorrhage, severe
Intestine: Diffuse transmural necrotizing enteritis, severe
Lungs: Multifocal necrotizing pneumonia, moderate, generalized
Lymph nodes: Diffuse necrotizing lymphadenitis, severe
All affected tissues in the capybara and cat were positive with IHC for Francisella tularensis.
Cat: Francisella tularensis cultured positive